Extracorporeal photopheresis (ECP) is a non-invasive treatment used to support patients with conditions such as cutaneous T-cell lymphoma, complications from organ transplants, and certain skin graft issues.

During the procedure, a small amount of your blood is drawn and passed through a machine that separates the white blood cells. These cells are treated with a light-sensitive medication and exposed to ultraviolet (UV) light, then returned to your body—helping target and eliminate diseased cells.

ECP is typically done over two consecutive days, with each session lasting about 3–4 hours. It’s an outpatient procedure, so no hospital stay is required. Treatment frequency varies based on your condition, ranging from weekly to monthly.