What is the most important information I should know about dihydroergotamine nasal?
Tell your doctor about all your other medicines. Some drugs should not be used with dihydroergotamine.
What is dihydroergotamine nasal?
Dihydroergotamine nasal is used to treat migraine headaches with or without aura in adults. Dihydroergotamine nasal will only treat a headache that has already begun. It will not prevent headaches or reduce the number of attacks.
Dihydroergotamine nasal should not be used to treat common tension headaches or any headache that seems to be different from your usual migraine headaches.
Dihydroergotamine nasal may also be used for purposes not listed in this medication guide.
What should I discuss with my healthcare provider before using dihydroergotamine nasal?
You should not use dihydroergotamine if you are allergic to it or similar medicines (ergotamine, ergonovine, methylergonovine, and others), or if you have:
- heart disease, angina (chest pain), blood circulation problems, coronary artery disease (hardening of the arteries), or history of a heart attack or stroke;
- uncontrolled high blood pressure;
- severe liver or kidney disease;
- a serious infection called sepsis; or
- if you have had vascular surgery.
Some drugs should not be used with dihydroergotamine. Your treatment plan may change if you also use:
- an antibiotic such as clarithromycin or erythromycin;
- antifungal medicine such as itraconazole or ketoconazole; or
- antiviral medicine for HIV or hepatitis C.
Tell your doctor if you have ever had:
- blood circulation problems in your arms, hands, legs, or feet;
- chest pain, shortness of breath;
- liver or kidney disease; or
- risk factors for coronary artery disease (high blood pressure, high cholesterol, diabetes, menopause, smoking, family history of coronary artery disease, being overweight, being over 40 and a man).
Dihydroergotamine can affect blood circulation to your uterus. Tell your doctor if you are pregnant or plan to become pregnant. Do not use this medicine if you are pregnant.
Do not breastfeed while using this medicine, and for at least 3 days after your last dose. Talk with your doctor about the best way to feed your baby.
How should I use dihydroergotamine nasal?
Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.
Dihydroergotamine nasal spray is absorbed quickly through your nasal passages and is for use only in the nose. The nasal spray liquid should not be injected into the body.
Your doctor may want to give your first dose of this medicine in a medical setting to quickly treat any serious side effects that occur.
You may need medical tests to check your heart function.
Store at room temperature away from moisture and heat. Do not keep this medicine in a refrigerator or freezer.
A Trudhesa vial should be thrown away 8 hours after it has been opened.
What happens if I miss a dose?
Dihydroergotamine is used when needed. If you are on a dosing schedule, skip any missed dose. Do not use two doses at one time.
Do not use more than 2 doses of Trudhesa within 24 hours or 3 doses within 7 days.
Do not use more than 3 mg of Migranal within 24 hours or 4 mg within 7 days.
What happens if I overdose?
Seek emergency medical attention if you think you have used too much of this medicine. An overdose can be fatal.
What should I avoid while using dihydroergotamine nasal?
Do not use dihydroergotamine nasal within 24 hours before or after using another migraine headache medicine, including:
- another ergot medicine such as ergotamine, ergonovine, methylergonovine; or
- almotriptan, eletriptan, frovatriptan, naratriptan, sumatriptan, or rizatriptan.
Grapefruit may interact with dihydroergotamine nasal and cause side effects. Avoid consuming grapefruit products.
What are the possible side effects of dihydroergotamine nasal?
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have:
-
signs of a blood clot --sudden numbness or weakness on one side of the body, problems with vision or speech, pain or swelling in one leg;
- stomach cramps, diarrhea that may be bloody;
- numbness or tingling in your fingers or toes;
- chest pain or tightness, shortness of breath;
- muscle pain in your arms or legs;
- leg weakness; or
- swelling or itching.
Common side effects may include:
- pain, bruising, swelling, or irritation where the medicine was applied;
- sleep problems (insomnia);
- dizziness;
- nausea, vomiting, diarrhea;
- runny nose;
- altered sense of taste; or
- soreness or irritation in your nose.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What other drugs will affect dihydroergotamine nasal?
Tell your doctor about all your current medicines. Many drugs can affect dihydroergotamine, especially:
- heart or blood pressure medication;
- nicotine gum or patches;
- an antidepressant; or
- medicine to treat an infection.
This list is not complete. Many drugs can affect dihydroergotamine. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here. Tell your doctor about all other medicines you use.
Where can I get more information?
Your doctor or pharmacist can provide more information about dihydroergotamine nasal.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Copyright 1996-2022 Cerner Multum, Inc. Version: 5.01. Revision date: 7/28/2022.
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